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Protein Stability Analysis: Ensuring Therapeutic and Functional Integrity
Protein stability analysis is a critical aspect of biopharmaceutical development, drug formulation, and biochemical research. It involves assessing the structural, chemical, and functional stability of proteins under various conditions to ensure their efficacy, safety, and shelf life.
What Is Protein Stability Analysis?
Proteins are sensitive biomolecules that can undergo denaturation, aggregation, oxidation, or degradation due to environmental stresses such as temperature, pH, light, or mechanical stress. Protein stability analysis aims to monitor these changes and predict the protein’s behavior during storage, formulation, and use.
Key objectives:
Determine thermal, chemical, and physical stability.
Identify degradation pathways.
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